Souris incoherente

Bonjour,
depuis quelque temps, ma souris est incohérente et mon pc se ralentit,ai fait un scan avec hijackthis voila le resultat et que dois je faire maintenant ? il y a t il des lignes suspects, merci de votre aide.
Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 20:06:45, on 24/06/2008
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP2 (6.00.2900.2180)
Boot mode: Normal

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
C:\WINDOWS\Explorer.EXE
C:\Program Files\Avira\AntiVir PersonalEdition Classic\sched.exe
C:\Program Files\Avira\AntiVir PersonalEdition Classic\avguard.exe
C:\Program Files\Avira\AntiVir PersonalEdition Classic\avgnt.exe
C:\WINDOWS\system32\rundll32.exe
C:\Program Files\Fichiers communs\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
C:\Program Files\Fichiers communs\Real\Update_OB\realsched.exe
C:\WINDOWS\system32\ctfmon.exe
C:\WINDOWS\system32\nvsvc32.exe
C:\Program Files\Logitech\MouseWare\system\em_exec.exe
C:\WINDOWS\System32\tcpsvcs.exe
C:\WINDOWS\System32\snmp.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Windows Live\Messenger\msnmsgr.exe
C:\Program Files\Opera\Opera.exe
C:\Program Files\Trend Micro\HijackThis\HijackThis.exe

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Bar = https://www.bing.com/?cc=fr&toHttps=1&redig=D4322FEE7CF74A348CB9CE970F098EF5
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = https://www.bing.com/?toHttps=1&redig=5FC791212101479BAFBE1A679848B1AF
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = https://www.msn.com/fr-fr/?redirfallthru=http%3a%2f%2fwww.msn.fr%2fimg%2ffr%2ffr-fr%2fmsger%2ftabs%2f_pictos%2fcoca%2fPictoCoke02.png%3f
R1 - HKCU\Software\Microsoft\Internet Explorer\SearchURL,(Default) = https://www.bing.com/?FORM=TOOLBR&cc=fr&toHttps=1&redig=4527FFF1C12746FC9EDB535C75E80ECC
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = 127.0.0.1;<local>
R0 - HKCU\Software\Microsoft\Internet Explorer\Toolbar,LinksFolderName = Liens
O2 - BHO: Yahoo! Toolbar Helper - {02478D38-C3F9-4EFB-9B51-7695ECA05670} - C:\Program Files\Yahoo!\Companion\Installs\cpn\yt.dll
O2 - BHO: Aide pour le lien d'Adobe PDF Reader - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Fichiers communs\Adobe\Acrobat\ActiveX\AcroIEHelper.dll
O2 - BHO: (no name) - {53707962-6F74-2D53-2644-206D7942484F} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O2 - BHO: SSVHelper Class - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files\Java\jre1.6.0_01\bin\ssv.dll
O2 - BHO: (no name) - {7E853D72-626A-48EC-A868-BA8D5E23E045} - (no file)
O2 - BHO: Windows Live Sign-in Helper - {9030D464-4C02-4ABF-8ECC-5164760863C6} - C:\Program Files\Fichiers communs\Microsoft Shared\Windows Live\WindowsLiveLogin.dll
O3 - Toolbar: Yahoo! Toolbar - {EF99BD32-C1FB-11D2-892F-0090271D4F88} - C:\Program Files\Yahoo!\Companion\Installs\cpn\yt.dll
O4 - HKLM\..\Run: [NvCplDaemon] RUNDLL32.EXE NvQTwk,NvCplDaemon initialize
O4 - HKLM\..\Run: [WinMsg] C:\WINDOWS\winmsgr.exe
O4 - HKLM\..\Run: [Workflow(2)] G:\install\Workflow.exe
O4 - HKLM\..\Run: [RecoverFromReboot] C:\WINDOWS\Temp\RecoverFromReboot.exe
O4 - HKLM\..\Run: [nwiz] nwiz.exe /install
O4 - HKLM\..\Run: [NvMediaCenter] RunDLL32.exe NvMCTray.dll,NvTaskbarInit
O4 - HKLM\..\Run: [Adobe Reader Speed Launcher] "C:\Program Files\Adobe\Reader 8.0\Reader\Reader_sl.exe"
O4 - HKLM\..\Run: [Logitech Utility] Logi_MwX.Exe
O4 - HKLM\..\Run: [avgnt] "C:\Program Files\Avira\AntiVir PersonalEdition Classic\avgnt.exe" /min
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKLM\..\Run: [TkBellExe] "C:\Program Files\Fichiers communs\Real\Update_OB\realsched.exe" -osboot
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O4 - HKUS\S-1-5-19\..\Run: [CTFMON.EXE] C:\WINDOWS\System32\CTFMON.EXE (User 'SERVICE LOCAL')
O4 - HKUS\S-1-5-20\..\Run: [CTFMON.EXE] C:\WINDOWS\System32\CTFMON.EXE (User 'SERVICE RÉSEAU')
O4 - HKUS\S-1-5-18\..\RunOnce: [tscuninstall] (User 'SYSTEM')
O4 - HKUS\.DEFAULT\..\RunOnce: [tscuninstall] (User 'Default user')
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_01\bin\npjpi160_01.dll
O9 - Extra 'Tools' menuitem: Console Java (Sun) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_01\bin\npjpi160_01.dll
O9 - Extra button: (no name) - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra 'Tools' menuitem: @xpsp3res.dll,-20001 - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O10 - Unknown file in Winsock LSP: c:\windows\system32\nwprovau.dll
O16 - DPF: {16BED5D9-AA6B-4A96-A134-C1958893490F} (VacPro.int_ver40v) - http://advnt01.com/dialer/intES_ver40v.CAB
O16 - DPF: {20A60F0D-9AFA-4515-A0FD-83BD84642501} (Checkers Class) - http://messenger.zone.msn.com/binary/msgrchkr.cab56986.cab
O16 - DPF: {5C051655-FCD5-4969-9182-770EA5AA5565} (Solitaire Showdown Class) - http://messenger.zone.msn.com/binary/SolitaireShowdown.cab56986.cab
O16 - DPF: {5ED80217-570B-4DA9-BF44-BE107C0EC166} (Windows Live Safety Center Base Module) - http://cdn.scan.onecare.live.com/resource/download/scanner/wlscbase9602.cab
O16 - DPF: {6414512B-B978-451D-A0D8-FCFDF33E833C} (WUWebControl Class) - http://update.microsoft.com/...
O16 - DPF: {67A5F8DC-1A4B-4D66-9F24-A704AD929EEE} (System Requirements Lab) - https://www.nvidia.com/content/DriverDownload/srl/2.0.0.1/sysreqlab2.cab
O16 - DPF: {6E32070A-766D-4EE6-879C-DC1FA91D2FC3} (MUWebControl Class) - http://update.microsoft.com/...
O16 - DPF: {C3F79A2B-B9B4-4A66-B012-3EE46475B072} (MessengerStatsClient Class) - http://messenger.zone.msn.com/binary/MessengerStatsPAClient.cab56907.cab
O16 - DPF: {F5A7706B-B9C0-4C89-A715-7A0C6B05DD48} (Minesweeper Flags Class) - http://messenger.zone.msn.com/binary/MineSweeper.cab56986.cab
O17 - HKLM\System\CCS\Services\Tcpip\..\{2128AFAD-E9CC-4277-979E-94B18929FC85}: NameServer = 194.117.200.10,194.117.200.15
O17 - HKLM\System\CS1\Services\Tcpip\..\{2128AFAD-E9CC-4277-979E-94B18929FC85}: NameServer = 194.117.200.10,194.117.200.15
O20 - Winlogon Notify: SMDEn - C:\WINDOWS\system32\m846lihs1846.dll (file missing)
O23 - Service: Avira AntiVir Personal – Free Antivirus Scheduler (AntiVirScheduler) - Avira GmbH - C:\Program Files\Avira\AntiVir PersonalEdition Classic\sched.exe
O23 - Service: Avira AntiVir Personal – Free Antivirus Guard (AntiVirService) - Avira GmbH - C:\Program Files\Avira\AntiVir PersonalEdition Classic\avguard.exe
O23 - Service: Apple Mobile Device - Apple, Inc. - C:\Program Files\Fichiers communs\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
O23 - Service: Command Service (cmdService) - Unknown owner - C:\WINDOWS\UGF0cmljaw\command.exe (file missing)
O23 - Service: Service de l'iPod (iPod Service) - Apple Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: NVIDIA Driver Helper Service (NVSvc) - NVIDIA Corporation - C:\WINDOWS\system32\nvsvc32.exe
O23 - Service: Sunbelt Personal Firewall 4 (SPF4) - Sunbelt Software - C:\Program Files\Sunbelt Software\Personal Firewall\kpf4ss.exe