VIRUS detecter par avast

Bonjour, a tous

je vous rederange car mon frere a un virus sur son ordinateur.

voila un rapport Hijackthis, es ce grave ?

Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 20:06:38, on 27/09/2008
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP2 (6.00.2900.2180)
Boot mode: Normal

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Alwil Software\Avast4\aswUpdSv.exe
C:\Program Files\Alwil Software\Avast4\ashServ.exe
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\Fichiers communs\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
C:\WINDOWS\system32\nvsvc32.exe
C:\WINDOWS\system32\PnkBstrA.exe
C:\WINDOWS\system32\wscntfy.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\system32\RUNDLL32.EXE
C:\Program Files\Java\jre1.6.0_05\bin\jusched.exe
C:\WINDOWS\SOUNDMAN.EXE
C:\Program Files\CyberLink DVD Solution\PowerDVD\PDVDServ.exe
C:\Program Files\iTunes\iTunesHelper.exe
C:\PROGRA~1\ALWILS~1\Avast4\ashDisp.exe
C:\Program Files\MSN Messenger\msnmsgr.exe
C:\Program Files\Messenger\msmsgs.exe
C:\Program Files\iPod\bin\iPodService.exe
C:\Program Files\Java\jre1.6.0_05\bin\jucheck.exe
C:\Program Files\Alwil Software\Avast4\ashMaiSv.exe
C:\Program Files\Alwil Software\Avast4\ashWebSv.exe
C:\Program Files\Mozilla Firefox\firefox.exe
C:\WINDOWS\system32\PnkBstrB.exe
c:\program files\internet explorer\iexplore.exe
C:\Program Files\Trend Micro\HijackThis\HijackThis.exe

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Bar = https://www.google.fr/?gws_rd=ssl
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.files-ftp.com/~unicorni/phpBB2/index.php
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://www.files-ftp.com/~unicorni/phpBB2/index.php
R0 - HKCU\Software\Microsoft\Internet Explorer\Toolbar,LinksFolderName = Liens
O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 5.0\Reader\ActiveX\AcroIEHelper.ocx
O2 - BHO: RealPlayer Download and Record Plugin for Internet Explorer - {3049C3E9-B461-4BC5-8870-4C09146192CA} - C:\Program Files\Real\RealPlayer\rpbrowserrecordplugin.dll
O2 - BHO: Spybot-S&D IE Protection - {53707962-6F74-2D53-2644-206D7942484F} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O2 - BHO: SSVHelper Class - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files\Java\jre1.6.0_05\bin\ssv.dll
O2 - BHO: (no name) - {7E853D72-626A-48EC-A868-BA8D5E23E045} - (no file)
O2 - BHO: solution Class - {99C6D1BB-7555-474C-91DA-D8FB62A9CC75} - C:\WINDOWS\system32\4T2bB3Xj.dll (file missing)
O4 - HKLM\..\Run: [NvCplDaemon] RUNDLL32.EXE C:\WINDOWS\system32\NvCpl.dll,NvStartup
O4 - HKLM\..\Run: [nwiz] nwiz.exe /install
O4 - HKLM\..\Run: [NvMediaCenter] RUNDLL32.EXE C:\WINDOWS\system32\NvMcTray.dll,NvTaskbarInit
O4 - HKLM\..\Run: [SunJavaUpdateSched] "C:\Program Files\Java\jre1.6.0_05\bin\jusched.exe"
O4 - HKLM\..\Run: [SoundMan] SOUNDMAN.EXE
O4 - HKLM\..\Run: [RemoteControl] "C:\Program Files\CyberLink DVD Solution\PowerDVD\PDVDServ.exe"
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\QTTask.exe" -atboottime
O4 - HKLM\..\Run: [iTunesHelper] "C:\Program Files\iTunes\iTunesHelper.exe"
O4 - HKLM\..\Run: [NBKeyScan] "C:\Program Files\Nero\Nero8\Nero BackItUp\NBKeyScan.exe"
O4 - HKLM\..\Run: [TkBellExe] "C:\Program Files\Fichiers communs\Real\Update_OB\realsched.exe" -osboot
O4 - HKLM\..\Run: [avast!] C:\PROGRA~1\ALWILS~1\Avast4\ashDisp.exe
O4 - HKCU\..\Run: [BgMonitor_{79662E04-7C6C-4d9f-84C7-88D8A56B10AA}] "C:\Program Files\Fichiers communs\Nero\Lib\NMBgMonitor.exe"
O4 - HKCU\..\Run: [msnmsgr] "C:\Program Files\MSN Messenger\msnmsgr.exe" /background
O4 - HKCU\..\Run: [MSMSGS] "C:\Program Files\Messenger\msmsgs.exe" /background
O4 - HKCU\..\Run: [SpybotSD TeaTimer] C:\Program Files\Spybot - Search & Destroy\TeaTimer.exe
O4 - Global Startup: Microsoft Office.lnk = C:\Program Files\Microsoft Office\Office10\OSA.EXE
O8 - Extra context menu item: E&xporter vers Microsoft Excel - res://C:\PROGRA~1\MICROS~2\Office10\EXCEL.EXE/3000
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_05\bin\ssv.dll
O9 - Extra 'Tools' menuitem: Console Java (Sun) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_05\bin\ssv.dll
O9 - Extra button: (no name) - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O9 - Extra 'Tools' menuitem: Spybot - Search & Destroy Configuration - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O12 - Plugin for .spop: C:\Program Files\Internet Explorer\Plugins\NPDocBox.dll
O14 - IERESET.INF: START_PAGE_URL=http://www.files-ftp.com/~unicorni/phpBB2/index.php
O15 - Trusted Zone: http://www.secuser.com
O16 - DPF: CabBuilder - http://kiw.imgag.com/imgag/kiw/toolbar/download/InstallerControl.cab
O16 - DPF: {20A60F0D-9AFA-4515-A0FD-83BD84642501} (Checkers Class) - http://messenger.zone.msn.com/binary/msgrchkr.cab56986.cab
O16 - DPF: {74D05D43-3236-11D4-BDCD-00C04F9A3B61} (HouseCall Control) - https://www.trendmicro.com/en_us/forHome/products/housecall.html
O16 - DPF: {C3F79A2B-B9B4-4A66-B012-3EE46475B072} (MessengerStatsClient Class) - http://messenger.zone.msn.com/binary/MessengerStatsPAClient.cab56907.cab
O23 - Service: Apple Mobile Device - Apple, Inc. - C:\Program Files\Fichiers communs\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
O23 - Service: avast! iAVS4 Control Service (aswUpdSv) - ALWIL Software - C:\Program Files\Alwil Software\Avast4\aswUpdSv.exe
O23 - Service: avast! Antivirus - ALWIL Software - C:\Program Files\Alwil Software\Avast4\ashServ.exe
O23 - Service: avast! Mail Scanner - ALWIL Software - C:\Program Files\Alwil Software\Avast4\ashMaiSv.exe
O23 - Service: avast! Web Scanner - ALWIL Software - C:\Program Files\Alwil Software\Avast4\ashWebSv.exe
O23 - Service: Service de l'iPod (iPod Service) - Apple Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: NVIDIA Display Driver Service (NVSvc) - NVIDIA Corporation - C:\WINDOWS\system32\nvsvc32.exe
O23 - Service: PnkBstrA - Unknown owner - C:\WINDOWS\system32\PnkBstrA.exe
O23 - Service: PnkBstrB - Unknown owner - C:\WINDOWS\system32\PnkBstrB.exe