Ordi lent et fichier qui n'ouvre pas

Bonjour j'ai un probleme de lenteur avec mon ordi depuis un certain et je ne suis plus capable de demarrer des applications microsoft office s.v.p. pouvez-vous m'aider ?

Logfile of HijackThis v1.99.1
Scan saved at 22:09:37, on 2007-03-24
Platform: Windows XP (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 (6.00.2600.0000)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Ahead\InCD\InCDsrv.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\Java\jre1.5.0_11\bin\jusched.exe
C:\WINDOWS\System32\LVCOMSX.EXE
C:\PROGRA~1\ALWILS~1\Avast4\ashDisp.exe
C:\Program Files\Fichiers communs\Real\Update_OB\realsched.exe
C:\Program Files\CyberLink DVD Solution\PowerDVD\PDVDServ.exe
C:\Program Files\QuickTime\qttask.exe
C:\Program Files\ScanSoft\OmniPageSE4.0\OpwareSE4.exe
C:\Program Files\Creative\MediaSource\RemoteControl\RcMan.exe
C:\PROGRA~1\INCRED~1\bin\IMApp.exe
C:\Program Files\Alwil Software\Avast4\aswUpdSv.exe
C:\Program Files\Alwil Software\Avast4\ashServ.exe
C:\WINDOWS\System32\CTSvcCDA.EXE
C:\Program Files\Fichiers communs\LightScribe\LSSrvc.exe
C:\WINDOWS\System32\nvsvc32.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Alwil Software\Avast4\ashWebSv.exe
C:\Program Files\Alwil Software\Avast4\ashMaiSv.exe
C:\Program Files\Fichiers communs\Microsoft Shared\VS7DEBUG\MDM.EXE
C:\Documents and Settings\stef\Bureau\HijackThis.exe

R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.warez.com/
R0 - HKCU\Software\Microsoft\Internet Explorer\Toolbar,LinksFolderName = Liens
O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 5.0\Reader\ActiveX\AcroIEHelper.ocx
O2 - BHO: SSVHelper Class - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files\Java\jre1.5.0_11\bin\ssv.dll
O3 - Toolbar: Yahoo! Toolbar - {EF99BD32-C1FB-11D2-892F-0090271D4F88} - C:\Program Files\Yahoo!\Companion\Installs\cpn\yt.dll
O3 - Toolbar: &Radio - {8E718888-423F-11D2-876E-00A0C9082467} - C:\WINDOWS\System32\msdxm.ocx
O4 - HKLM\..\Run: [CTHelper] CTHELPER.EXE
O4 - HKLM\..\Run: [AsioReg] REGSVR32.EXE /S CTASIO.DLL
O4 - HKLM\..\Run: [SBDrvDet] C:\Program Files\Creative\SB Drive Det\SBDrvDet.exe /r
O4 - HKLM\..\Run: [UpdReg] C:\WINDOWS\UpdReg.EXE
O4 - HKLM\..\Run: [NvCplDaemon] RUNDLL32.EXE C:\WINDOWS\System32\NvCpl.dll,NvStartup
O4 - HKLM\..\Run: [nwiz] nwiz.exe /install
O4 - HKLM\..\Run: [SunJavaUpdateSched] "C:\Program Files\Java\jre1.5.0_11\bin\jusched.exe"
O4 - HKLM\..\Run: [LVCOMSX] C:\WINDOWS\System32\LVCOMSX.EXE
O4 - HKLM\..\Run: [LogitechVideoRepair] C:\Program Files\Logitech\Video\ISStart.exe
O4 - HKLM\..\Run: [avast!] C:\PROGRA~1\ALWILS~1\Avast4\ashDisp.exe
O4 - HKLM\..\Run: [TkBellExe] "C:\Program Files\Fichiers communs\Real\Update_OB\realsched.exe" -osboot
O4 - HKLM\..\Run: [RemoteControl] "C:\Program Files\CyberLink DVD Solution\PowerDVD\PDVDServ.exe"
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKLM\..\Run: [iTunesHelper] "C:\Program Files\iTunes\iTunesHelper.exe"
O4 - HKLM\..\Run: [NvMediaCenter] RUNDLL32.EXE C:\WINDOWS\System32\NvMcTray.dll,NvTaskbarInit
O4 - HKLM\..\Run: [SSBkgdUpdate] "C:\Program Files\Fichiers communs\Scansoft Shared\SSBkgdUpdate\SSBkgdupdate.exe" -Embedding -boot
O4 - HKLM\..\Run: [OpwareSE4] "C:\Program Files\ScanSoft\OmniPageSE4.0\OpwareSE4.exe"
O4 - HKLM\..\Run: [MSConfig] C:\WINDOWS\PCHealth\HelpCtr\Binaries\MSConfig.exe /auto
O4 - HKCU\..\Run: [IncrediMail] C:\Program Files\IncrediMail\bin\IncMail.exe /c
O4 - HKCU\..\Run: [RemoteCenter] C:\Program Files\Creative\MediaSource\RemoteControl\RcMan.exe
O4 - HKCU\..\Run: [WMPNSCFG] C:\Program Files\Windows Media Player\WMPNSCFG.exe
O4 - HKCU\..\Run: [LogitechSoftwareUpdate] "C:\Program Files\Logitech\Video\ManifestEngine.exe" boot
O4 - Global Startup: Adobe Gamma Loader.lnk = ?
O8 - Extra context menu item: E&xporter vers Microsoft Excel - res://C:\PROGRA~1\MICROS~2\OFFICE11\EXCEL.EXE/3000
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.5.0_11\bin\ssv.dll
O9 - Extra 'Tools' menuitem: Console Java (Sun) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.5.0_11\bin\ssv.dll
O9 - Extra button: Recherche - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~2\OFFICE11\REFIEBAR.DLL
O9 - Extra button: PartyPoker.com - {B7FE5D70-9AA2-40F1-9C6B-12A255F085E1} - C:\Program Files\PartyGaming\PartyPoker\RunApp.exe
O9 - Extra 'Tools' menuitem: PartyPoker.com - {B7FE5D70-9AA2-40F1-9C6B-12A255F085E1} - C:\Program Files\PartyGaming\PartyPoker\RunApp.exe
O9 - Extra button: Related - {c95fe080-8f5d-11d2-a20b-00aa003c157a} - C:\WINDOWS\web\related.htm
O9 - Extra 'Tools' menuitem: Show &Related Links - {c95fe080-8f5d-11d2-a20b-00aa003c157a} - C:\WINDOWS\web\related.htm
O12 - Plugin for .spop: C:\Program Files\Internet Explorer\Plugins\NPDocBox.dll
O16 - DPF: {33331111-1111-1111-1111-611111193423} -
O16 - DPF: {33331111-1111-1111-1111-611111193429} -
O16 - DPF: {33331111-1111-1111-1111-615111193427} -
O17 - HKLM\System\CCS\Services\Tcpip\..\{4F5ECBA8-62C8-4F25-9DEA-15379BB97FD1}: NameServer = 85.255.116.25,85.255.112.94
O17 - HKLM\System\CCS\Services\Tcpip\..\{638A5351-6039-4310-9494-FCB81A91A3D3}: NameServer = 85.255.116.25,85.255.112.94
O17 - HKLM\System\CCS\Services\Tcpip\..\{D457EFD3-1F4F-4D96-8317-AA9E58EA4FF4}: NameServer = 85.255.116.25,85.255.112.94
O18 - Protocol: msnim - {828030A1-22C1-4009-854F-8E305202313F} - "C:\PROGRA~1\MSNMES~1\msgrapp.dll" (file missing)
O20 - Winlogon Notify: WgaLogon - C:\WINDOWS\
O21 - SSODL: WPDShServiceObj - {AAA288BA-9A4C-45B0-95D7-94D524869DB5} - C:\WINDOWS\system32\WPDShServiceObj.dll
O23 - Service: avast! iAVS4 Control Service (aswUpdSv) - Unknown owner - C:\Program Files\Alwil Software\Avast4\aswUpdSv.exe
O23 - Service: avast! Antivirus - Unknown owner - C:\Program Files\Alwil Software\Avast4\ashServ.exe
O23 - Service: avast! Mail Scanner - Unknown owner - C:\Program Files\Alwil Software\Avast4\ashMaiSv.exe" /service (file missing)
O23 - Service: avast! Web Scanner - Unknown owner - C:\Program Files\Alwil Software\Avast4\ashWebSv.exe" /service (file missing)
O23 - Service: Creative Service for CDROM Access - Creative Technology Ltd - C:\WINDOWS\System32\CTSvcCDA.EXE
O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - C:\Program Files\Fichiers communs\InstallShield\Driver\11\Intel 32\IDriverT.exe
O23 - Service: InCD Helper (InCDsrv) - Nero AG - C:\Program Files\Ahead\InCD\InCDsrv.exe
O23 - Service: iPod Service - Apple Computer, Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: LightScribeService Direct Disc Labeling Service (LightScribeService) - Hewlett-Packard Company - C:\Program Files\Fichiers communs\LightScribe\LSSrvc.exe
O23 - Service: NVIDIA Display Driver Service (NVSvc) - NVIDIA Corporation - C:\WINDOWS\System32\nvsvc32.exe